Welcome to the TOTAL trial website,
On this webpage you can find general information on Congenital Diaphragmatic Hernia (CDH) for both healthcare professionals as well as parents. ‚Ä®Furthermore we explain the potential advantages of an intervention before birth, which is now under investigation in two trials.‚Ä® 
This site will be updated regularly as research in CDH is continuously providing new insights. However if there are any inconsistencies or additional questions you can always contact us
Kind regards,
the TOTAL trial participating centers
BREAKING: 3 May 2019
On 2nd of May the recruitment for the TOTAL trial MODERATE has ended. This was after recruiting the planned study population of 196 cases. The outcomes will only be available 6 months after the birth of the last baby that was randomised, we expect this to be in 8 months. Treatment of fetuses with moderate hypoplasia is experimental, and until the results of the study become available, this experimental therapy should not be offered to patients carrying a fetus with moderate hypoplasia anymore. The findings of the study will determine whether this should be done at all.
BREAKING: 10 March 2020
The recruitment for the SEVERE trial has ended. The results are being prepared for dissemination. 
This research was supported by funding of the European Commission under the Sixth Framework Programme  'EuroSTEC'-project (LSHB-CT-2006-037409); www.eurostec.eu (end date: November 2011)