Welcome to the TOTAL trial website,
On this webpage you can find general information on Congenital Diaphragmatic Hernia (CDH) for both healthcare professionals as well as parents. ‚Ä®Furthermore we explain the potential advantages of an intervention before birth, which is now under investigation in two trials.‚Ä® 
This site will be updated regularly as research in CDH is continuously providing new insights. However if there are any inconsistencies or additional questions you can always contact us
Kind regards,
the TOTAL trial participating centers
Update: statement after interim analysis of moderate trial (03/10/2018).
The TOTAL trial for fetuses with moderate hypoplasia is still recruiting patients and is close to reaching the final sample size of the study (196 patients). The current recruitment rate is 1.5 patients per month and based on this we expect to finish the moderate trial within the next year. The next interim analysis (178 patients) is expected June 2019. The DMSC emphasizes that FETO is still an investigational procedure and encourages referring centres and FETO centres to maintain or improve current recruitment.

This research was supported by funding of the European Commission under the Sixth Framework Programme  'EuroSTEC'-project (LSHB-CT-2006-037409); www.eurostec.eu (end date: November 2011)