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Welcome to the TOTAL trial website,
 
On this webpage you can find general information on Congenital Diaphragmatic Hernia (CDH) for both healthcare professionals as well as parents. ‚Ä®Furthermore we explain the potential advantages of an intervention before birth, which is now under investigation in two trials.‚Ä® 
 
This site will be updated regularly as research in CDH is continuously providing new insights. However if there are any inconsistencies or additional questions you can always contact us
 
Kind regards,
 
the TOTAL trial participating centers
 
Update: statement 11 April 2019
 
The DSMC members have met on the 5th April 2019 and determined that based on the available literature there is still equipoise regarding FETO treatment in CDH infants at risk for both SEVERE and MODERATE lung hypoplasia.  Both trials are ongoing and actively recruiting patients 
 
This research was supported by funding of the European Commission under the Sixth Framework Programme  'EuroSTEC'-project (LSHB-CT-2006-037409); www.eurostec.eu (end date: November 2011)